Smokers Thin Due Lack of Oxygen

Many smokers who do not want to quit smoking because of reasonable weight will go up when he did not smoke. Though body lean smokers actually result from lack of oxygen.

This was conveyed by DR. dr. H. Ari Fahrial Sham, SpPH-KGEH, MMB, FINASIM, FACP Session after the ceremony and the Promotion of Doctoral Dissertation in the Faculty of medicine, entitled Development of Molecular Pathophysiology Gaster Rat Mucosal Lesions in Chronic Systemic Hypoxia: Overview of Expression of Hypoxia Inducible Factor-1α, Heat Shock Factor-1 and Heat Shock Protein 70, Jakarta, Friday (07/15/2011).

DR Ari convey when someone is in the altitude and hypoxia (oxygen deficiency) then he will tend to experience weight loss.

"One is, I think it also explains why smokers weight decreased. The first may be due to decreased appetite, but also smokers relative lack of oxygen," explains Dr. Ari from the Department of Medicine Faculty of medicine / RSCM.

According to Dr. Ari, when someone smokes in a stuffy room (closed) then the oxygen is reduced to reduce appetite.

Oxygen balance can be disrupted either because they increase the levels of CO can come from cigarette smoke.

"Well, this is what I proved (in the dissertation research), that if there was a hypoxia (lack of oxygen) then there will be what we call the HIF-1alfa," said Dr. Ari.

1alfa is a HIF-induced gene in these conditions, where these genes also affect other genes, one gene of appetite (leptin gene) that cause decreased appetite.

"Well this phenomenon that I pull one of them explaining to the audience that when we are deprived of oxygen the body will lose weight," explained Dr. Ari.